Ablacta dietary Supplements



“Ablacta” is a natural supplement formulation designed to assist fecal transplantation therapies or introduction (weaning) diets. The details are described below in the “Modality of Action” section. All formulations contain 2 components which can work in combination to rebalance an intestinal dysbiosis:

  • High Quality Alpha Lactalbumin (ALAC)
  • Soluble Fibers: FOS and Inulin

The “Plus” formulation has anti inflammatory properties (Boswellic acid) and contains the amino acid L-Glutamine capable of reducing intestinal permeability. It is recommended in cases associated with higher levels of intestinal permeability, in particular inflammatory bowel diseases.

Recommended Posology

Dissolve sachet content in 1 ounce / 20-30 ml of water and drink on an empty stomach 20 minutes before eating. Twice daily; before breakfast and dinner. If FMT capsules are being used take Ablacta together with the capsules.

Allergen Information

Contains milk derivatives.



Modality of Action – The idea behind Ablacta

The idea for the use of Alpha Lactalbumin (ALAC) with soluble fibers to help correct a dysbiosis was an idea of Prof. Dr. Paolo Mainardi: He was the first proponent of this formulation with his product Serplus.

ALAC is a milk serum protein, particularly present in our milk. In our colostrum it represents 40% of proteins, in adult milk it decreases to 2 g/l. Its role is to activate protective and absorption processes in the intestine, through these actions it modulates cerebral development.

ALAC is particularly rich in tryptophan, an essential amino acid, which is limited in our diet and the only precursor of serotonin. Oral uptake of ALAC are effectively capable of increasing the plasmatic level of tryptophan. Its uptake within the brain leads to the cerebral synthesis of serotonin. This data was confirmed in several studies (1). Serotonin, present in blood is produced by 95% in the intestine, starting from tryptophan. Cerebral melatonin is synthesized from serotonin. Neither serotonin or melatonin can pass the blood brain barrier, tryptophan can. 

The direct intake of Tryptophan do not produce an increase of its plasmatic level, in there the capacity of absorbing entire proteins and free amino acids by the intestine is lost during the postnatal development.

Cerebral absorbed Tryptophan is also involved in the cerebral synthesis of neuropeptides, such as leptin, noradrenaline and NPY. These neuropeptides play an important role in controlling cerebral activity, neuronal plasticity depends on their level, that is the capacity of our central nervous system to repair itself. Many neurological symptoms can be tied to low levels of these neuropeptides.

The soluble fibers are not split by enzymes in the stomach, reaching the colon where they ferment producing short chain fatty acids (e.g. butyrate) that constitute the main nutrient of the intestinal cells, that can so better response to the stimulation by ALAC.

What is the difference between “Ablacta” and “Serplus Complex”?

Serplus complex is a supplement that was created by Dr. Paolo Mainardi similar to Ablacta. They both contain ALAC, inulin and FOS as their main active ingredients. Ablacta does not contain the artificial sweetener stevia derivate, the polysorbate 80 emulsifier and the maltodextrin carrier, because they are not considered necessary for an effective use of the product.

  1. https://www.ncbi.nlm.nih.gov/pubmed/15883425, https://www.ncbi.nlm.nih.gov/pubmed/12036812, https://academic.oup.com/ajcn/article/71/6/1536/4729518

Additional information


25 Sach. Ablacta, 25 Sach. Ablacta Plus